March 26, 2021

preprint on the immune response after the first dose of Pfizer vaccine in those with and without prior infection

A new preprint from researchers at the universities of Sheffield, Oxford, Liverpool, Newcastle and Birmingham looks at the T-cell and antibody responses in health care workers after the first dose of the Pfizer vaccine, and is able to compare these immune responses in those who had prior infection with SARS-CoV-2 and those who did not. Journalists dialled in to hear from the authors of the study explain their findings and answer any questions about the work.

Please note this data is a preprint, so it is early work that has not yet been through peer-review and is not published in a journal.

Speakers included:

Dr Thushan de Silva, Senior Clinical Lecturer in Infectious Diseases and Honorary Consultant Physician in Infectious Diseases, University of Sheffield and Lead Academic of this study

Prof Susanna Dunachie, NIHR Global Research Professor at the Nuffield Department of Medicine, University of Oxford and Chief Investigator of the study at the university

Prof Paul Klenerman, Sidney Truelove Professor of Gastroenterology at the at the Nuffield Department of Medicine, University of Oxford and Chief Investigator of the study at the university

Prof Miles Carroll, Professor of Virology at the Nuffield Department of Medicine, University of Oxford

This Briefing was accompanied by an SMC Roundup of Comments.