Building on Sally Davies’s vision for integrating genomics into every aspect of the NHS, Dr. Sullivan can discuss some of the latest genomics and population-based genomic analysis is starting to play in understanding the genetic determinants of Alzheimer’s disease. read more
The BMJ has published a study investigating the effectiveness of cancer drugs approved by the European Medicines Agency (EMA).
The National Crime Agency reported that at least 60 people have died in the UK in the last eight months after taking the strong painkiller fentanyl.
Publishing in Reproduction researchers examine mouse brain structure and behaviour following prenatal exposure to paracetamol. read more
The Academy of Medical Sciences has published a new report entitled, ‘Enhancing the use of scientific evidence to judge the potential benefits and harms of medicines’.
Publishing in The Lancet researchers report that long-term daily aspirin use is linked to a higher than expected risk of bleeding in adults aged 75 or over. The scientists claim that proton-pump inhibitors should be co-prescribed in this age group to reduce the risk of bleeds. read more
We already know aspirin and other blood thinners can increase the risk of bleeding. Aspirin is often prescribed after a heart attack or stroke to reduce the risk of further heart attacks and strokes. read more
At the American Society of Clinical Oncology (ASCO), scientists presented results from an early clinical trial of an ovarian cancer drug that could potentially shrink tumours. read more
Publishing in the British Journal of Pharmacology scientists report an association between slightly increased risk of cardiovascular malformations in infants and maternal fluoxetine use. read more
A new observational study published in the BMJ investigates the association between painkillers and myocardial infarction risk. read more
The Cancer Drugs Fund (CDF) was launched in England in 2010 to provide patients with access to anti-cancer drugs not available through the NHS because the drugs had not been appraised, were in the process of being appraised, or had been appraised but not recommended by the National Institute of Health and Care Excellence (NICE). read more
A paper published in Cell investigated the effects of a peptide to target senescent cells in mice and reported improved kidney function and restoration of fur, suggesting that this could lead to a therapy with potential to reverse certain aspects of ageing. read more
The National Institute for Health and Care Excellence (NICE) has published new guidance which recommends Cetuximab and panitumumab, for previously untreated metastatic colorectal cancer, be moved from the Cancer Drugs Fund into routine use. read more
It has been announced that Solanezumab, an experimental Alzheimer’s treatment from Eli Lilly & Co, failed to slow the progression of the neurodegenerative disease. read more
A group of researchers have published their work in The BMJ examining the effect of non-steroidal anti-inflammatory drugs (NSAIDs) and report that use of such drugs can increase the risk of heart failure. read more
The effect of a parent’s paracetamol use before and after a child’s birth and the child’s behavioural problems is a analysed in a paper published in JAMA Pediatrics in which the authors report that children who were exposed to paracetamol prenatally were at increased risk of multiple behavioural difficulties. read more
Inflammation of airways is often found in asthmatic patients and a group of researchers publishing in the Lancet Respiratory Medicine journal have reported that a drug taken as a pill alongside standard inhaler treatment was associated with reduce asthmatic inflammation, increase lung function and improved asthma control in a group of people with severe asthma. read more
A group of researchers publishing in the journal Addiction have performed a systematic review of evidence supporting the efficacy of the drug nalmefene, approved in the UK for the treatment of alcohol dependence. They report problems in the methodology of clinical trials upon which this approval was based, and suggest that their conclusions may create dilemmas for clinicians prescribing the drug. read more
Cannabis is a class B drug in the UK but is in use for therapeutic purposes in a number of countries for various diseases, and a paper published in the journal Scientific Reports has reported that e-cigarette devices could be effective in administering therapeutic doses of the drug. read more
A study in mice published in the journal Nature has reported that a metabolite from the breakdown of ketamine is responsible for antidepressant effects of the drug. read more