Two studies published in Cell Host & Microbe look at the gut microbiome and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).   … read more

A study published in Science Advances looks at antibody responses against human microbiota flagellins in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) … read more

The National Institute for Health and Care Excellence (NICE) has published its updated guideline on the diagnosis and management of myalgic … read more

The National Institute for Health and Care Excellence (NICE) have announced today that they have decided to pause publication of … read more

NICE have released an updated draft guideline for the diagnosis and management of myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome (ME/CFS). … read more

Research published in PNAS suggests a potential biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Prof Chris Ponting, Chair of Medical … read more

Reactions to a letter from the Health Research Authority (HRA) to Norman Lamb MP on an inquiry into the PACE … read more

Despite tentative evidence that the immune system might play a role in chronic fatigue syndrome (CFS) the underlying biology of … read more

A reanalysis of the PACE trial is published in BMC Psychology. A roundup accompanied this analysis.   This review was … read more

A reanalysis of the PACE trial is published in BMC Psychology.  read more

Last week we ran press conferences on climate change and CFS/ME. The subjects are complex and contentious, and there is always the potential for jarring or simplistic headlines and strong reactions from the vocal critics of research in these fields. But it was the criticism from within the scientific community that we had not anticipated. read more

The Lightning Process is a controversial treatment that is sometimes used for children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME). read more

In a new study, and despite strong initial scepticism, researchers publishing in the Journal of Archives of Disease in Childhood report that a training course alongside specialist care has proved to be an effective treatment for chronic fatigue syndrome (CFS)/myalgic encdephalomyelitis (ME). read more

In a new study, and despite their strong initial scepticism, researchers publishing in the Journal of Archives of Disease in Childhood report that a training course alongside specialist care appears to be effective treatment for children with chronic fatigue syndrome (CFS)/myalgic encdephalomyelitis (ME). read more

Researchers publishing in Proceedings of the National Academy of Sciences (PNAS) report a link between chronic fatigue syndrome and cytokine concentrations that correlate with the disease’s severity. read more

The Journal of Healthy Psychology has published a special issue focusing on the PACE trial – originally published in The Lancet (2011). read more

Researchers publishing in The Lancet present their findings from a randomised controlled trial they conducted to test the efficacy and safety of graded exercise delivered as guided self-help, for the treatment of chronic fatigue syndrome. read more

In England up to two in 100 children have Chronic Fatigue Syndrome (CFS/ME), the illness means they are unable to go to school or do other activities for more than three months. In fact 1% of secondary school children miss a day a week or more because of it. Unfortunately controversy rages around the illness and the treatment. Most children will recover if they receive specialist treatment; however, there is very limited specialist care in the UK and approximately 90% of children live too far away to receive the treatment they need. Cognitive Behavioural Therapy (CBT) is known to be effective for children and a very successful trial in the Netherlands showed it can be delivered over the internet, meaning children can be helped wherever they live. However, we do not know if the results can be replicated in the UK so researchers, amidst rising tension from some people who do not support treatments such as CBT or Graded Exercise Therapy, are now starting a large clinical trial to test whether this treatment would work in the UK and should be available on the NHS. read more

A group of researchers publishing in the journal Proceedings of the National Academy of Sciences (PNAS) have examined the metabolic features of patients with chronic fatigue syndrome (CFS/ME) and report a number of differences in various metabolic pathways. read more

CFS/ME affects around 250,000 people in the UK and in severe cases results in patients being mostly bedridden and unable to do more than minimal daily tasks. The PACE trial, published in 2011, suggested that Cognitive Behaviour Therapy (CBT) and Graded Exercise Therapy (GET) were moderately effective ways of treating people. A subsequent PACE trial follow-up study, published in The Lancet Psychiatry in January 2015, attempted to explain how and why these therapies work and what the implications were. Now, a follow-up study, also published in The Lancet Psychiatry, has assessed the participants’ health in the long-term, and asks whether their current state of health, two and a half years after entering the trial, has been affected by which treatment they received in the trial. read more