There have been news reports that babies have been born in the UK following mitochondrial replacement therapy (MRT).   Dr … read more

A study published in PLOS Biology looks at the safety of spindle transfer for preventing transfer of mitochondrial mutations from … read more

Research, published in Current Biology, reports that a protein has been identified in fruit flies that can be targeted to … read more

Research published in Science shows that mitochondria interact with cell nucleus’ in ways previously unseen in humans. Matching mitochondrial DNA … read more

Reactions to a piece published in NEJM which discusses which women stand to benefit from mitochondrial donation.    Dr Hansong … read more

Expert reaction to media reports that a US scientist talking at a public meeting at Harvard University has said he … read more

Reactions to news of the birth of a baby through mitochondrial DNA transfer in Greece. A spokesperson for the Human … read more

Low-level lead exposure and mortality in US adults is examined in a population-based cohort study, published in The Lancet. read more

The HFEA has granted doctors at Newcastle Fertility Centre permission to perform mitochondrial replacement therapy on two women who are at risk of passing on mitochondrial disease to their offspring.  read more

Scientists publishing in Protein & Cell report the first study using base editing to correct a mutation in human embryos, for the disease beta-thalassemia. read more

A genetic mutation implicated in hypertrophic cardiomyopathy – a common heritable heart condition – has been corrected in preimplantation human embryos using the CRISPR/Cas9 genome editing technique, as reported by scientists in Nature. read more

Courts have ruled against continuing life-preserving treatment for 11 month old Charlie Gard. Since this ruling, offers of support and experimenyal treatment have come from both the US and Italy. read more

A fire has raged through a 24-storey west London residential building, several fatalities have been confirmed and more than 50 people have been taken to hospital.
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Published in Reproductive Biomedicine Online, scientists have described the technique they used to create the first live birth after oocyte spindle transfer to prevent transmission of the mitochondrial disease, Leigh syndrome. read more

The HFEA has approved a licence application for Newcastle University to use mitochondrial donation therapy in treating mitochondrial disease. read more

The National Academies of Sciences (NAS) and National Academy of Medicine (NAM) have published a new report, Human Genome Editing: Science, Ethics, and Governance. read more

A baby has been born to a previously infertile couple in Ukraine using pronuclear transfer, a new type of “three-person IVF”. read more

The HFEA decided to permit the clinical use of mitochondrial donation techniques in the UK. read more

Researchers, publishing in the journal Nature, have reported on a study which used mitochondrial donation therapy to replace pathogenic mitochondrial DNA mutations in human ooctyes with mitochondrial DNA from healthy donor eggs. The researchers report the potential of mitochondrial replacement therapy (MRT) to reduce the transfer of mitochondrial disease from mother to child. read more

An independent expert panel, convened by the Human Fertilisation and Embryology Authority (HFEA), have published their fourth scientific review into the latest evidence on the safety and efficacy of mitochondrial donation techniques, recommending that those techniques be approved for “cautious use” in “specific circumstances”. These comments accompanied a press briefing. read more